The Science Behind Breathe'N'Roll™
Breathe'N'Roll™ is grounded in pioneering scientific research led by Dr. Naum Goldstein, PhD, a world-renowned biophysicist. His decades of work on the role of exogenous superoxide oxygen from the surrounding air in the vitality of animals and humans, alongside broader studies on the vomeronasal organ (VNO), inspire our safe, innovative wellness product.
Scientific Basis and Hypothesis
Dr. Naum Goldstein’s research, published in respected scientific journals, investigates the potential role of the VNO — a chemosensory structure in the nasal cavity — in receiving signals from exogenous superoxide oxygen present in the surrounding air that may influence well-being*.
His studies suggest that this superoxide could be vital, with animal research showing significant effects when deprived. Broader scientific explorations by other researchers, including studies on pheromone detection, further support the VNO’s potential role in reflex responses. Some research also suggests that VNO dysfunction may contribute to specific olfactory impairments, termed "olfactory color blindness", where individuals lose the ability to perceive certain smells — such as musky or floral scents—due to selective receptor damage**.
This phenomenon is linked to early stages of certain neurological conditions, though this remains unproven and is not linked to Breathe'N'Roll™’s effects. These findings inspire our innovative approach.
* Goldstein N, Arshavskaya TV. Is atmospheric superoxide vitally necessary? Accelerated death of animals in a quasi neutral electric atmosphere. Z Naturforsch C. 1997;52(5–6):396–404. Read full study.
** Bhatnagar KP, Smith TD. The human vomeronasal organ. Part V. An interpretation of its discovery by Ruysch, Jacobson, or Kölliker, with an English translation of Kölliker (1877). Anat Rec B New Anat. 2003;270(1):4–15. Read full study.
Hydrogen Peroxide Pathway
In nature, exogenous superoxide from the surrounding air may transform into hydrogen peroxide (H₂O₂) upon contact with the nasal mucosa*, where it is rapidly broken down by the enzyme superoxide dismutase into water and oxygen within microseconds**. This process is hypothesized to generate an electrochemical impulse, potentially stimulating the VNO and triggering reflex responses in the brain***.
This natural process is a scientific hypothesis and not a claimed effect of Breathe'N'Roll™. Dr. Goldstein’s insights into this mechanism, supported by emerging research, inspired the inclusion of food-grade H₂O₂ in Breathe'N'Roll™, formulated to mimic this process safely and support natural vitality.
* Goldstein N. Reactive oxygen species as essential components of ambient air. Biochemistry (Moscow). 2002;67(2):161–170. Read full study.
** Oboti L, Peretto P. How neurogenesis finds its place in a hardwired sensory system. Front Neurosci. 2014;8:102. Read full study.
*** Smith TD, Bhatnagar KP. Histological definition of the vomeronasal organ in humans and chimpanzees, with a comparison to other primates. Anat Rec. 2002;267(2):166–176. Read full study.
Legacy & Clinical Foundations
Breathe'N'Roll™ builds on 20+ years of real-world experience.
Breathe'N'Roll™ draws from the practical legacy of Parkon® — a pharmaceutical nasal spray developed by Dr. Naum Goldstein and introduced into clinical use by Alexander Terterov, founder of Breathe'N'Roll™.
Over two decades, Parkon® was used in neurology and psychiatry across Russia, Armenia, Ukraine, and Georgia. With thousands of patients treated and no reported adverse effects, its benefits — such as enhanced cognitive clarity, reduced emotional reactivity, and improved resilience — were consistently observed in clinical settings.
This real-world experience directly inspired the development of Breathe'N'Roll™ as a safe, non-pharmaceutical wellness product for everyday neurosensory support.
Safety and Innovation
Breathe'N'Roll™ employs food-grade hydrogen peroxide (H₂O₂), carefully formulated to be well below FDA safety limits for nasal sprays. This safe, non-systemic experience is validated by our FDA/DSHEA consultant with over 12 years of expertise, building on Dr. Goldstein’s rigorous scientific standards.
